Iridium target manufacturers understand that agglomerated iridium metal is neither biologically useful nor harmful because it does not react with biological tissue. Like most metals, iridium metal fines are dangerous. Such powders can irritate tissues and burn easily in the air.

Iridium target manufacturers have learned that the high melting point and high stability of iridium make it useful in many special occasions, but the brittleness and high temperature loss of iridium limit its application to a certain extent. The earliest application of iridium was as a pen tip material, and later it was proposed for injection needles, balance blades, compass brackets, and electrical contacts. Iridium crucibles can be used to grow refractory oxide crystals. The crucibles can work for thousands of hours at 2100-2200 °C and are important precious metal utensils.
The high-temperature oxidation resistance and thermoelectric properties of iridium make iridium/iridium-rhodium thermocouple the only precious metal temperature measurement material that can measure high temperatures up to 2100 °C in the atmosphere; it can be used as a container material for radioactive heat sources; anodized iridium film is a Prospective electrochromic materials.